Pharmaceuticals giant Almac will create almost 350 jobs in Co Armagh in the next five years as the firm ramps up its international sales.
Announcing the project, Enterprise Minister Arlene Foster said the investment represented a major boost to the economy of the province.
"Almac is one of Northern Ireland's most successful indigenous companies and a globally respected brand," she said.
"This significant investment will enable the company to expand the range of services it can offer, allowing it to respond to key trends within the pharmaceutical industry and enhance its market-leading position."
Based at Portadown, Almac operates in the pharmaceutical and biotechnology sectors providing services including drug discovery, diagnostics, research and development as well as manufacture of active pharmaceutical ingredients, formulation development and clinical trials.